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Correlation of cell‐surface CD8 levels with function, phenotype and transcriptome of naive CD8 T cells

We have previously demonstrated co‐receptor level‐associated functional heterogeneity in apparently homogeneous naive peripheral CD4 T cells, dependent on MHC‐mediated tonic signals. Maturation pathways can differ between naive CD4 and naive CD8 cells, so we tested whether the latter showed similar...

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Détails bibliographiques
Publié dans:Immunology
Auteurs principaux: Balyan, Renu, Gund, Rupali, Chawla, Amanpreet Singh, Khare, Satyajeet P., Pradhan, Saurabh J., Rane, Sanket, Galande, Sanjeev, Durdik, Jeannine Marie, George, Anna, Bal, Vineeta, Rath, Satyajit
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418459/
https://ncbi.nlm.nih.gov/pubmed/30556901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13036
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