Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy Metabolism

Chronic low-grade inflammation and increased serum levels of the cytokine IL-6 accompany obesity. For brain-produced IL-6, the mechanisms by which it controls energy balance and its role in obesity remain unclear. Here, we show that brain-produced IL-6 is decreased in obese mice and rats in a neuroa...

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Vydáno v:Cell Rep
Hlavní autoři: Mishra, Devesh, Richard, Jennifer E., Maric, Ivana, Porteiro, Begona, Häring, Martin, Kooijman, Sander, Musovic, Saliha, Eerola, Kim, López-Ferreras, Lorena, Peris, Eduard, Grycel, Katarzyna, Shevchouk, Olesya T., Micallef, Peter, Olofsson, Charlotta S., Wernstedt Asterholm, Ingrid, Grill, Harvey J., Nogueiras, Ruben, Skibicka, Karolina P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418345/
https://ncbi.nlm.nih.gov/pubmed/30865890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.02.044
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