Antioxidant treatment induces reductive stress associated with mitochondrial dysfunction in adipocytes

β-Adrenergic stimulation of adipose tissue increases mitochondrial density and activity (browning) that are associated with improved whole-body metabolism. Whereas chronically elevated levels of reactive oxygen species (ROS) in adipose tissue contribute to insulin resistance, transient ROS elevation...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Peris, Eduard, Micallef, Peter, Paul, Alexandra, Palsdottir, Vilborg, Enejder, Annika, Bauzá-Thorbrügge, Marco, Olofsson, Charlotta S., Wernstedt Asterholm, Ingrid
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378980/
https://ncbi.nlm.nih.gov/pubmed/30559295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004253
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