Circadian and wake-dependent changes in human plasma polar metabolites during prolonged wakefulness: A preliminary analysis

Establishing circadian and wake-dependent changes in the human metabolome are critical for understanding and treating human diseases due to circadian misalignment or extended wake. Here, we assessed endogenous circadian rhythms and wake-dependent changes in plasma metabolites in 13 participants (4 f...

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Publicado no:Sci Rep
Main Authors: Grant, Leilah K., Ftouni, Suzanne, Nijagal, Brunda, De Souza, David P., Tull, Dedreia, McConville, Malcolm J., Rajaratnam, Shantha M. W., Lockley, Steven W., Anderson, Clare
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418225/
https://ncbi.nlm.nih.gov/pubmed/30872634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40353-8
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