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Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner

Leishmania parasites experience variable nutrient levels as they cycle between the extracellular promastigote stage in the sandfly vector and the obligate intracellular amastigote stage in the mammalian host. Here we show that the surface expression of three Leishmania mexicana hexose and myo-inosit...

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Main Authors: Vince, James E., Tull, Dedreia, Landfear, Scott, McConville, Malcolm J.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592973/
https://ncbi.nlm.nih.gov/pubmed/21447343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2011.02.003
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