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Dual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells
Carcinoma metastasis is triggered by a subpopulation of circulating tumor cells (CTCs). And single immune checkpoint therapy is not good enough to inhibit CTC-induced metastasis. Here, we demonstrate that simultaneously blocking CD274 (programmed death ligand 1, PD-L1 or B7-H1) and CD47 checkpoints...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418176/ https://ncbi.nlm.nih.gov/pubmed/30872703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40241-1 |
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