Highly interacting regions of the human genome are enriched with enhancers and bound by DNA repair proteins

In specific cases, chromatin clearly forms long-range loops that place distant regulatory elements in close proximity to transcription start sites, but we have limited understanding of many loops identified by Chromosome Conformation Capture (such as Hi-C) analyses. In efforts to elucidate their cha...

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Udgivet i:Sci Rep
Main Authors: Sobhy, Haitham, Kumar, Rajendra, Lewerentz, Jacob, Lizana, Ludvig, Stenberg, Per
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418152/
https://ncbi.nlm.nih.gov/pubmed/30872630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40770-9
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