Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis

The lack of biomarkers for early diagnosis, clinical stratification and to monitor treatment response has hampered the development of new therapies for amyotrophic lateral sclerosis (ALS), a clinically heterogeneous neurodegenerative disorder with a variable site of disease initiation and rate of pr...

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Published in:Sci Rep
Main Authors: Leoni, Emanuela, Bremang, Michael, Mitra, Vikram, Zubiri, Irene, Jung, Stephan, Lu, Ching-Hua, Adiutori, Rocco, Lombardi, Vittoria, Russell, Claire, Koncarevic, Sasa, Ward, Malcolm, Pike, Ian, Malaspina, Andrea
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418138/
https://ncbi.nlm.nih.gov/pubmed/30872628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40632-4
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