Intratumor heterogeneity inferred from targeted deep sequencing as a prognostic indicator

Tumor genetic heterogeneity may underlie poor clinical outcomes because diverse subclones could be comprised of metastatic and drug resistant cells. Targeted deep sequencing has been used widely as a diagnostic tool to identify actionable mutations in cancer patients. In this study, we evaluated the...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Oh, Bo Young, Shin, Hyun-Tae, Yun, Jae Won, Kim, Kyu-Tae, Kim, Jinho, Bae, Joon Seol, Cho, Yong Beom, Lee, Woo Yong, Yun, Seong Hyeon, Park, Yoon Ah, Park, Yeon Hee, Im, Young-Hyuck, Lee, Jeeyun, Joung, Je-Gun, Kim, Hee Cheol, Park, Woong-Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418103/
https://ncbi.nlm.nih.gov/pubmed/30872730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41098-0
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