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Genomic Characterization and Comparison of Multi-Regional and Pooled Tumor Biopsy Specimens

A single tumor biopsy specimen is typically used in cancer genome studies. However, it may represent incompletely the underlying mutational and transcriptional profiles of tumor biology. Multi-regional biopsies have the advantage of increased sensitivity for genomic profiling, but they are not cost-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Joung, Je-Gun, Bae, Joon Seol, Kim, Sang Cheol, Jung, HyunChul, Park, Woong-Yang, Song, Sang-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807092/
https://ncbi.nlm.nih.gov/pubmed/27010638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152574
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