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NRP-1 interacts with GIPC1 and SYX to activate p38 MAPK signaling and cancer stem cell survival

Epidermal cancer stem cells (ECS cells) comprise a limited population of cells that form aggressive, rapidly growing, and highly vascularized tumors. VEGF-A/NRP-1 signaling is a key driver of the ECS cell phenotype and aggressive tumor formation. However, relatively less is known regarding the downs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Carcinog
Hauptverfasser: Grun, Daniel, Adhikary, Gautam, Eckert, Richard L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417965/
https://ncbi.nlm.nih.gov/pubmed/30456845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22943
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