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VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors

We identify a limited subpopulation of epidermal cancer stem cells (ECS cells), in squamous cell carcinoma, that form rapidly growing, invasive and highly vascularized tumors, as compared with non-stem cancer cells. These ECS cells grow as non-attached spheroids, and display enhanced migration and i...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Grun, D, Adhikary, G, Eckert, RL
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959993/
https://ncbi.nlm.nih.gov/pubmed/26804163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.507
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