Oral Cavity Squamous Cell Carcinoma Xenografts Retain Complex Genotypes and Intertumor Molecular Heterogeneity

Herein, we report an oral cavity squamous cell carcinoma (OCSCC) patient-derived xenograft (PDX) platform, with genomic annotation useful for co-clinical trial and mechanistic studies. Genomic analysis included whole-exome sequencing (WES) and transcriptome sequencing (RNA-seq) on 16 tumors and matc...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Campbell, Katie M., Lin, Tianxiang, Zolkind, Paul, Barnell, Erica K., Skidmore, Zachary L., Winkler, Ashley E., Law, Jonathan H., Mardis, Elaine R., Wartman, Lukas D., Adkins, Douglas R., Chernock, Rebecca D., Griffith, Malachi, Uppaluri, Ravindra, Griffith, Obi L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417872/
https://ncbi.nlm.nih.gov/pubmed/30134176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.058
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky