Reduction of CFU-GM and circulating hematopoietic progenitors in a subgroup of children with chronic neutropenia associated with severe infections and delayed recovery

Myelopoiesis was evaluated in 66 pediatric patients with chronic neutropenia who were positive for anti-neutrophil antibodies (median age at diagnosis: 11 months, median neutrophil count at diagnosis: 419/μl). Other causes of neutropenia were excluded. Bone marrow morphology, clonogenic tests and/or...

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Veröffentlicht in:PLoS One
Hauptverfasser: Timeus, Fabio, Crescenzio, Nicoletta, Foglia, Luiselda, Doria, Alessandra, Stillitano, Maria Giuseppina, Garelli, Emanuela, Mazzone, Raffaela, Vivalda, Laura, Vallero, Stefano, Ramenghi, Ugo, Saracco, Paola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417780/
https://ncbi.nlm.nih.gov/pubmed/30870474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213782
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