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Integrating germline and somatic variation information using genomic data for the discovery of biomarkers in prostate cancer

BACKGROUND: Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading cause of cancer-related deaths among men in the United States. High-throughput genotyping has enabled discovery of germline genetic susceptibility variants (herein referred to as germline mutations) asso...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Mamidi, Tarun Karthik Kumar, Wu, Jiande, Hicks, Chindo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417124/
https://ncbi.nlm.nih.gov/pubmed/30871495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5440-8
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