ロード中...

Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double stranded DNA

Zta is a bZIP transcription factor (TF) in the Epstein-Barr virus that binds unmethylated and methylated DNA sequences. Substitution of cysteine 189 of Zta to serine (Zta(C189S)) results in a virus that is unable to execute the lytic cycle which was attributed to a change in binding to methylated DN...

詳細記述

保存先:
書誌詳細
出版年:Biochem Biophys Res Commun
主要な著者: Ray, Sreejana, Tillo, Desiree, Assad, Nima, Ufot, Aniekanabasi, Deppmann, Christopher, Durell, Stewart R., Porollo, Aleksey, Vinson, Charles
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417095/
https://ncbi.nlm.nih.gov/pubmed/29772230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.05.080
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!