In vivo compartmental kinetics of Plasmodium falciparum histidine-rich protein II in the blood of humans and in BALB/c mice infected with a transgenic Plasmodium berghei parasite expressing histidine-rich protein II

BACKGROUND: The Plasmodium falciparum histidine-rich protein II (PfHRP2) is a common biomarker used in malaria rapid diagnostic tests (RDTs), but can persist in the blood for up to 40 days following curative treatment. The persistence of PfHRP2 presents a false positive limitation to diagnostic inte...

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Publicado en:Malar J
Main Authors: Poti, Kristin E., Balaban, Amanda E., Pal, Priya, Kobayashi, Tamaki, Goldberg, Daniel E., Sinnis, Photini, Sullivan, David J.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416945/
https://ncbi.nlm.nih.gov/pubmed/30866956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2712-3
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