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Inhibition of antithrombin by Plasmodium falciparum histidine-rich protein II

Histidine-rich protein II (HRPII) is an abundant protein released into the bloodstream by Plasmodium falciparum, the parasite that causes the most severe form of human malaria. Here, we report that HRPII binds tightly and selectively to coagulation-active glycosaminoglycans (dermatan sulfate, hepara...

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Detalhes bibliográficos
Main Authors: Ndonwi, Matthew, Burlingame, Oname O., Miller, Aaron S., Tollefsen, Douglas M., Broze, George J., Goldberg, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122953/
https://ncbi.nlm.nih.gov/pubmed/21511958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-326876
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