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GRIBCG: a software for selection of sgRNAs in the design of balancer chromosomes
BACKGROUND: Balancer chromosomes are tools used by fruit fly geneticists to prevent meiotic recombination. Recently, CRISPR/Cas9 genome editing has been shown capable of generating inversions similar to the chromosomal rearrangements present in balancer chromosomes. Extending the benefits of balance...
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| Опубликовано в: : | BMC Bioinformatics |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416924/ https://ncbi.nlm.nih.gov/pubmed/30866794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2712-x |
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