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GRIBCG: a software for selection of sgRNAs in the design of balancer chromosomes

BACKGROUND: Balancer chromosomes are tools used by fruit fly geneticists to prevent meiotic recombination. Recently, CRISPR/Cas9 genome editing has been shown capable of generating inversions similar to the chromosomal rearrangements present in balancer chromosomes. Extending the benefits of balance...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Merritt, Brian B., Cheung, Lily S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416924/
https://ncbi.nlm.nih.gov/pubmed/30866794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2712-x
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