Performance evaluation of commercial library construction kits for PCR-based targeted sequencing using a unique molecular identifier

BACKGROUND: Target enrichment is a critical component of targeted deep next-generation sequencing for the cost-effective and sensitive detection of mutations, which is predominantly performed by either hybrid selection or PCR. Despite the advantages of efficient enrichment, PCR-based methods preclud...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Chung, Jongsuk, Lee, Ki-Wook, Lee, Chung, Shin, Seung-Ho, Kyung, Sungkyu, Jeon, Hyo-Jeong, Kim, Sook-Young, Cho, Eunjung, Yoo, Chang Eun, Son, Dae-Soon, Park, Woong-Yang, Park, Donghyun
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416880/
https://ncbi.nlm.nih.gov/pubmed/30871467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5583-7
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