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Staphylococcus aureus–induced endothelial permeability and inflammation are mediated by microtubule destabilization

Staphylococcus aureus is a major etiological agent of sepsis and induces endothelial cell (EC) barrier dysfunction and inflammation, two major hallmarks of acute lung injury. However, the molecular mechanisms of bacterial pathogen–induced EC barrier disruption are incompletely understood. Here, we i...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Karki, Pratap, Ke, Yunbo, Tian, Yufeng, Ohmura, Tomomi, Sitikov, Albert, Sarich, Nicolene, Montgomery, Christopher P., Birukova, Anna A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416444/
https://ncbi.nlm.nih.gov/pubmed/30622143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004030
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