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Staphylococcus aureus–induced endothelial permeability and inflammation are mediated by microtubule destabilization

Staphylococcus aureus is a major etiological agent of sepsis and induces endothelial cell (EC) barrier dysfunction and inflammation, two major hallmarks of acute lung injury. However, the molecular mechanisms of bacterial pathogen–induced EC barrier disruption are incompletely understood. Here, we i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Karki, Pratap, Ke, Yunbo, Tian, Yufeng, Ohmura, Tomomi, Sitikov, Albert, Sarich, Nicolene, Montgomery, Christopher P., Birukova, Anna A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416444/
https://ncbi.nlm.nih.gov/pubmed/30622143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004030
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