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A polybasic motif in alternatively spliced KChIP2 isoforms prevents Ca(2+) regulation of Kv4 channels

The Kv4 family of A-type voltage-gated K(+) channels regulates the excitability in hippocampal pyramidal neuron dendrites and are key determinants of dendritic integration, spike timing-dependent plasticity, long-term potentiation, and learning. Kv4.2 channel expression is down-regulated following h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Murphy, Jonathan G., Hoffman, Dax A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416424/
https://ncbi.nlm.nih.gov/pubmed/30622142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006549
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