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A polybasic motif in alternatively spliced KChIP2 isoforms prevents Ca(2+) regulation of Kv4 channels

The Kv4 family of A-type voltage-gated K(+) channels regulates the excitability in hippocampal pyramidal neuron dendrites and are key determinants of dendritic integration, spike timing-dependent plasticity, long-term potentiation, and learning. Kv4.2 channel expression is down-regulated following h...

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Vydáno v:J Biol Chem
Hlavní autoři: Murphy, Jonathan G., Hoffman, Dax A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416424/
https://ncbi.nlm.nih.gov/pubmed/30622142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006549
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