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Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors
Protein sequences of members of the plasminogen activation system are present throughout the entire vertebrate phylum. This important and well-described proteolytic cascade is governed by numerous protease–substrate and protease–inhibitor interactions whose conservation is crucial to maintaining unc...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416416/ https://ncbi.nlm.nih.gov/pubmed/30651349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005419 |
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