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Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk
Platelets contract forcefully after their activation, contributing to the strength and stability of platelet aggregates and fibrin clots during blood coagulation. Viscoelastic approaches can be used to assess platelet-induced clot strengthening, but they require thrombin and fibrin generation and ar...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416331/ https://ncbi.nlm.nih.gov/pubmed/30867419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09150-9 |
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