The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling

Fibro/Adipogenic Progenitors (FAPs) define a stem cell population playing a pro-regenerative role after muscle damage. When removed from their natural niche, FAPs readily differentiate into adipocytes or fibroblasts. This digressive differentiation potential, which is kept under tight control in the...

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Vydáno v:Sci Rep
Hlavní autoři: Reggio, Alessio, Spada, Filomena, Rosina, Marco, Massacci, Giorgia, Zuccotti, Alessandro, Fuoco, Claudia, Gargioli, Cesare, Castagnoli, Luisa, Cesareni, Gianni
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416262/
https://ncbi.nlm.nih.gov/pubmed/30867438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39538-y
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