The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells

Glioblastoma multiform (GBM) is the most common brain tumor characterized by a dismal prognosis. GBM cancer stem cells (gCSC) or tumor-initiating cells are the cell population within the tumor-driving therapy resistance and recurrence. While temozolomide (TMZ), an alkylating agent, constitutes the f...

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Vydáno v:Cell Death Dis
Hlavní autoři: Mazor, Gal, Levin, Liron, Picard, Daniel, Ahmadov, Ulvi, Carén, Helena, Borkhardt, Arndt, Reifenberger, Guido, Leprivier, Gabriel, Remke, Marc, Rotblat, Barak
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416247/
https://ncbi.nlm.nih.gov/pubmed/30867410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1477-5
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