AKF-PD alleviates diabetic nephropathy via blocking the RAGE/AGEs/NOX and PKC/NOX Pathways

Diabetic nephropathy (DN) is a major complication of diabetes. Currently, drugs are not available to effectively control the disease. Fluorofenidone (AKF-PD) is a recently developed drug; it possesses activities in reducing DN progression in preclinical research. Nonetheless, its renal protection an...

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Vydáno v:Sci Rep
Hlavní autoři: Qin, Jiao, Peng, Zhangzhe, Yuan, QiongJing, Li, Qian, Peng, Yu, Wen, Rui, Hu, Zhaolan, Liu, Jun, Xia, Xiongfang, Deng, Hong, Xiong, Xuan, Hu, Jinyue, Tao, Lijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416244/
https://ncbi.nlm.nih.gov/pubmed/30867431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36344-w
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