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Ginseng metabolite Protopanaxadiol interferes with lipid metabolism and induces ER stress and p53 activation to promote cancer cell death

Protopanaxadiol (PPD), a ginseng metabolite generated by the gut bacteria, was shown to induce colorectal cancer cell death and enhance the anticancer effect of chemotherapeutic agent 5-FU. However, the mechanism by which PPD promotes cancer cell death is not clear. In this manuscript, we showed tha...

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Vydáno v:Phytother Res
Hlavní autoři: Jin, Hong Ri, Du, Charles H, Wang, Chong-Zhi, Yuan, Chun-Su, Du, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416078/
https://ncbi.nlm.nih.gov/pubmed/30537241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ptr.6249
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