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Synthesis of protopanaxadiol derivatives and evaluation of their anticancer activities
Protopanaxadiol (PPD), an aglycon of ginseng saponins, has shown anticancer activity in previous studies. Here we report the semi-synthesis of 9 PPD derivatives with acetyl substitutions. Subsequently, the antiproliferative effects of these 9 analogs on different human cancer cell lines were investi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992804/ https://ncbi.nlm.nih.gov/pubmed/20926945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e32833fde29 |
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