NEMO Peptide Inhibits the Growth of Pancreatic Ductal Adenocarcinoma by Blocking NF-κB Activation

NF-κB essential modulator (NEMO) binds and regulates IκB kinase (IKK) and is required for NF-κB activation. The NEMO-binding domain peptide (NBDP) of IKK was found to inhibit NF-κB activation and promote apoptosis in cancer cells. Studies have shown that constitutive NF-κB activation, one of the sig...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Zhuang, Zhuonan, Li, Hao, Lee, Harold, Aguilar, Mitzi, Gocho, Takashi, Ju, Huaiqiang, Iida, Tomonori, Ling, Jianhua, Fu, Jie, Wu, Min, Sun, Yichen, Lu, Yu, Chiao, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415976/
https://ncbi.nlm.nih.gov/pubmed/28951128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.09.018
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