Knockout of microRNA-21 attenuates alcoholic hepatitis through the VHL/NF-κB signaling pathway in hepatic stellate cells

microRNA-21 (miRNA) is one of the most abundant miRNAs in chronic liver injuries including alcoholic liver injury. Previous studies have demonstrated that miR-21 plays a role in inflammation in the liver and functions in hepatic stellate cells (HSCs), which reside in the perisinusoidal space between...

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Udgivet i:Am J Physiol Gastrointest Liver Physiol
Main Authors: Wu, Nan, McDaniel, Kelly, Zhou, Tianhao, Ramos-Lorenzo, Sugeily, Wu, Chaodong, Huang, Li, Chen, Demeng, Annable, Tami, Francis, Heather, Glaser, Shannon, Alpini, Gianfranco, Meng, Fanyin
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415712/
https://ncbi.nlm.nih.gov/pubmed/29848019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00111.2018
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