Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells

Substance P (SP) is involved in the proliferation of cholangiocytes in bile duct ligated (BDL) mice and human cholangiocarcinoma growth by interacting with the neurokinin-1 receptor (NK-1R). To identify whether SP regulates liver fibrosis during cholestasis, wild type (WT) or NK-1R knockout (NK-1R(−...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Hepatology
Главные авторы: Wan, Ying, Meng, Fanyin, Wu, Nan, Zhou, Tianhao, Venter, Julie, Francis, Heather, Kennedy, Lindsey, Glaser, Trenton, Bernuzzi, Francesca, Invernizzi, Pietro, Glaser, Shannon, Huang, Qiaobing, Alpini, Gianfranco
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519428/
https://ncbi.nlm.nih.gov/pubmed/28256736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29138
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы