Anti-inflammatory drug use and ovarian cancer risk by COX1/COX2 expression and infiltration of tumor-associated macrophages

BACKGROUND: NSAID use may affect ovarian cancer risk via prostaglandin synthesis and tumor-associated macrophage (TAM) infiltration. We evaluated if associations between aspirin or non-aspirin NSAID use and ovarian cancer risk differed by tumor expression of prostaglandin-related (COX1, COX2) and TA...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Barnard, Mollie E., Hecht, Jonathan L., Rice, Megan S., Gupta, Mamta, Harris, Holly R., Eliassen, A. Heather, Rosner, Bernard A., Terry, Kathryn L., Tworoger, Shelley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415678/
https://ncbi.nlm.nih.gov/pubmed/30377203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-18-0346
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