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Lifestyle and reproductive factors and ovarian cancer risk by p53 and MAPK expression

BACKGROUND: One model of ovarian cancer development model divides tumors into two types. Type I tumors are characterized by KRAS and BRAF mutations, which can activate mitogen-activated protein kinase (MAPK). Type II tumors are characterized by tubal precursor lesions with p53 mutations. We evaluate...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Harris, Holly R., Rice, Megan S., Shafrir, Amy L., Poole, Elizabeth M., Gupta, Mamta, Hecht, Jonathan L., Terry, Kathryn L., Tworoger, Shelley S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993043/
https://ncbi.nlm.nih.gov/pubmed/29133366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-17-0609
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