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Non-transpeptidase binding arylthioether β-Lactams active against Mycobacterium tuberculosis and Moraxella catarrhalis

The prevalence of drug resistance in both clinical and community settings as a consequence of alterations of biosynthetic pathways, enzymes or cell wall architecture is a persistent threat to human health. We have designed, synthesized, and tested a novel class of monocyclic β-lactams that carry an...

詳細記述

保存先:
書誌詳細
出版年:Bioorg Med Chem
主要な著者: Beck, Tim N., Lloyd, Dina, Kuskovsky, Rostislav, Minah, Jeanette, Arora, Kriti, Plotkin, Balbina J., Green, Jacalyn M., Boshoff, Helena I., Barry, Clifton, Deschamps, Jeffrey, Konaklieva, Monika I.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415315/
https://ncbi.nlm.nih.gov/pubmed/25549898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.11.025
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