Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential

Macrophages are responsible for innate and adaptive immune response activation necessary for eliminating infections. Optimal activation of macrophages to phagocytize Mycobacterium tuberculosis is critical in anti-mycobacterial defense. Here, we identified a novel Rv3463 hypothetical protein that ind...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Park, Hye-Soo, Back, Yong Woo, Shin, Ki-Won, Bae, Hyun Shik, Lee, Kang-In, Choi, Han-Gyu, Choi, Seunga, Lee, Hwang-Ho, Choi, Chul Hee, Park, Jeong-Kyu, Kim, Hwa-Jung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414722/
https://ncbi.nlm.nih.gov/pubmed/30862819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38982-0
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