Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential

Macrophages are responsible for innate and adaptive immune response activation necessary for eliminating infections. Optimal activation of macrophages to phagocytize Mycobacterium tuberculosis is critical in anti-mycobacterial defense. Here, we identified a novel Rv3463 hypothetical protein that ind...

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Pubblicato in:Sci Rep
Autori principali: Park, Hye-Soo, Back, Yong Woo, Shin, Ki-Won, Bae, Hyun Shik, Lee, Kang-In, Choi, Han-Gyu, Choi, Seunga, Lee, Hwang-Ho, Choi, Chul Hee, Park, Jeong-Kyu, Kim, Hwa-Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414722/
https://ncbi.nlm.nih.gov/pubmed/30862819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38982-0
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