A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the formation of toxic amyloid-β (Aβ) oligomers and plaques. Considering that Aβ misfolding and aggregation precedes the progressive development of cognitive impairment in AD, investigating a therapeutic means by c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Yang, Seung-Hoon, Shin, Jisu, Shin, Naewoo Neo, Hwang, Ji-Hyun, Hong, Sung-Chul, Park, Keunwan, Lee, Jae Wook, Lee, Sejin, Baek, Seungyeop, Kim, Kyeonghwan, Cho, Illhwan, Kim, YoungSoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414664/
https://ncbi.nlm.nih.gov/pubmed/30862818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40205-5
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge