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Primary lung cancer samples cultured under microenvironment-mimetic conditions enrich for mesenchymal stem-like cells that promote metastasis

The tumor microenvironment (TME) is composed of a heterogeneous biological ecosystem of cellular and non-cellular elements including transformed tumor cells, endothelial cells, immune cells, activated fibroblasts or myofibroblasts, stem and progenitor cells, as well as the cytokines and matrix that...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saforo, Douglas, Omer, Linda, Smolenkov, Andrei, Barve, Aditya, Casson, Lavona, Boyd, Nolan, Clark, Geoffrey, Siskind, Leah, Beverly, Levi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414636/
https://ncbi.nlm.nih.gov/pubmed/30862796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40519-4
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