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Crotoxin promotes macrophage reprogramming towards an antiangiogenic phenotype

Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated b...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: de Araújo Pimenta, Luciana, de Almeida, Maíra Estanislau S., Bretones, Marisa Langeani, Cirillo, Maria Cristina, Curi, Rui, Sampaio, Sandra Coccuzzo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414609/
https://ncbi.nlm.nih.gov/pubmed/30862840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40903-0
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