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Crotoxin promotes macrophage reprogramming towards an antiangiogenic phenotype

Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: de Araújo Pimenta, Luciana, de Almeida, Maíra Estanislau S., Bretones, Marisa Langeani, Cirillo, Maria Cristina, Curi, Rui, Sampaio, Sandra Coccuzzo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414609/
https://ncbi.nlm.nih.gov/pubmed/30862840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40903-0
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