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Reprogramming of pro-inflammatory human macrophages to an anti-inflammatory phenotype by bile acids

Cholestasis is caused by autoimmune reactions, drug-induced hepatotoxicity, viral infections of the liver and the obstruction of bile ducts by tumours or gallstones. Cholestatic conditions are associated with impaired innate and adaptive immunity, including alterations of the cellular functions of m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wammers, Marianne, Schupp, Anna-Kathrin, Bode, Johannes G., Ehlting, Christian, Wolf, Stephanie, Deenen, René, Köhrer, Karl, Häussinger, Dieter, Graf, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762890/
https://ncbi.nlm.nih.gov/pubmed/29321478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18305-x
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