HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide

Mutations in the HNF4A gene cause MODY1 and are associated with an increased risk of Type 2 diabetes mellitus. On the other hand, incretins are hormones that potentiate reductions in blood glucose levels. Given the established role of incretin-based therapy to treat diabetes and metabolic disorders,...

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Udgivet i:Sci Rep
Main Authors: Girard, Romain, Darsigny, Mathieu, Jones, Christine, Maloum-Rami, Faïza, Gélinas, Yves, Carpentier, André C., Laplante, Mathieu, Perreault, Nathalie, Boudreau, François
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414548/
https://ncbi.nlm.nih.gov/pubmed/30862908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41061-z
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