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PTMselect: optimization of protein modifications discovery by mass spectrometry

Discovery of protein modification sites relies on protein digestion by proteases and mass spectrometry (MS) identification of the modified peptides. Depending on proteases used and target protein sequence, this method yields highly variable coverage of modification sites. We introduce PTMselect, a d...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Perchey, Renaud T., Tonini, Laure, Tosolini, Marie, Fournié, Jean-Jacques, Lopez, Frédéric, Besson, Arnaud, Pont, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414543/
https://ncbi.nlm.nih.gov/pubmed/30862887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40873-3
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