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PTMselect: optimization of protein modifications discovery by mass spectrometry

Discovery of protein modification sites relies on protein digestion by proteases and mass spectrometry (MS) identification of the modified peptides. Depending on proteases used and target protein sequence, this method yields highly variable coverage of modification sites. We introduce PTMselect, a d...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Perchey, Renaud T., Tonini, Laure, Tosolini, Marie, Fournié, Jean-Jacques, Lopez, Frédéric, Besson, Arnaud, Pont, Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414543/
https://ncbi.nlm.nih.gov/pubmed/30862887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40873-3
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