Fish Cholesterol 25-Hydroxylase Inhibits Virus Replication via Regulating Interferon Immune Response or Affecting Virus Entry

Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-induced gene that catalyzes the oxidation of cholesterol to 25-hydroxycholesterol (25HC), which exerts broad-spectrum antiviral function. To investigate the roles of fish CH25H in Singapore grouper iridovirus (SGIV) and red-spotted grouper ne...

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Publicado en:Front Immunol
Autores principales: Zhang, Ya, Wang, Liqun, Huang, Xiaohong, Wang, Shaowen, Huang, Youhua, Qin, Qiwei
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414437/
https://ncbi.nlm.nih.gov/pubmed/30894855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00322
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