Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms

Cholesterol 25-hydroxylase (CH25H) as an interferon-stimulated gene (ISG) has recently been shown to exert broad antiviral activity through the production of 25-hydroxycholesterol (25HC), which is believed to inhibit the virus-cell membrane fusion during viral entry. However, little is known about t...

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Publicado no:Sci Rep
Main Authors: Chen, Yongzhi, Wang, Shanshan, Yi, Zhaohong, Tian, Huabin, Aliyari, Roghiyh, Li, Yanhua, Chen, Gang, Liu, Ping, Zhong, Jin, Chen, Xinwen, Du, Peishuang, Su, Lishan, Qin, F. Xiao-Feng, Deng, Hongyu, Cheng, Genhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252895/
https://ncbi.nlm.nih.gov/pubmed/25467815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07242
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