Longitudinal Analysis of Tear Cathepsin S Activity Levels in Male Non-Obese Diabetic Mice Suggests its Potential as an Early Stage Biomarker of Sjögren’s Syndrome

CONTEXT: Cathepsin S (CTSS) activity is elevated in Sjögren’s Syndrome (SS) patient tears. OBJECTIVE: To evaluate longitudinal expression of tear and tissue CTSS activity relative to other disease indicators in Non-Obese Diabetic (NOD) mice. METHODS: CTSS activity was measured in tears and lacrimal...

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Bibliographic Details
Published in:Biomarkers
Main Authors: Janga, Srikanth R., Shah, Mihir, Ju, Yaping, Meng, Zhen, Edman, Maria, Hamm-Alvarez, Sarah F.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414277/
https://ncbi.nlm.nih.gov/pubmed/30126300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1354750X.2018.1514656
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