Omega-3 fatty acids suppress Fusobacterium nucleatum–induced placental inflammation originating from maternal endothelial cells

Fusobacterium nucleatum is an oral anaerobe prevalent in intrauterine infection associated with a wide spectrum of adverse pregnancy outcomes. We demonstrate here that F. nucleatum triggers placental inflammation through maternal, rather than paternal, TLR4-mediated signaling. Elimination of TLR4 fr...

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Библиографические подробности
Опубликовано в: :JCI Insight
Главные авторы: Garcia-So, Jeewon, Zhang, Xinwen, Yang, Xiaohua, Rubinstein, Mara Roxana, Mao, De Yu, Kitajewski, Jan, Liu, Kang, Han, Yiping W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413831/
https://ncbi.nlm.nih.gov/pubmed/30728337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125436
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